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Article

The relative contributions of infectious and mitotic spread to HTLV-1 persistence

2019-10-09

Abstract excerpt

Human T-lymphotropic virus type-1 (HTLV-1) persists within hosts via infectious spread ( de novo infection) and mitotic spread (infected cell proliferation), creating a population structure of multiple clones (infected cell populations with identical genomic proviral integration sites). The relative contributions of infectious and mitotic spread to HTLV-1 persistence are unknown, and will determine the efficacy o...

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Identifiers and source

Literature Corpus work
8e9d7ef7-96cd-53fb-9502-5bb7185b3b67
DOI
10.1101/799197
Open publication

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