Article

Human Parental Relatedness through Time - Detecting Runs of Homozygosity in Ancient DNA

2020-06-01

Abstract excerpt

At present day, human parental relatedness varies substantially across the globe, but little is known about the past. Here we use ancient DNA to provide new insights, leveraging that parental relatedness leaves traces in the offspring’s genome in the form of runs of homozygosity. We present a method to identify such runs in low-coverage ancient DNA data using linkage information from a reference panel of modern ha...

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Literature Corpus work: 8e6fc70f-d030-578f-8ca5-cba74695ddd0
DOI: 10.1101/2020.05.31.126912

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