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Article

Reconstructing the history of founder events using genome-wide patterns of allele sharing across individuals.

PLoS genetics - 1 Jun 2022

Tournebize Rémi, Chu Gillian, Moorjani Priya

Abstract excerpt

Founder events play a critical role in shaping genetic diversity, fitness and disease risk in a population. Yet our understanding of the prevalence and distribution of founder events in humans and other species remains incomplete, as most existing methods require large sample sizes or phased genomes. Thus, we developed ASCEND that measures the correlation in allele sharing between pairs of individuals across the...

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Identifiers

PMID: 35737729
DOI: 10.1371/journal.pgen.1010243
PMCID: PMC9223333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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