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Article

Joint estimation of relatedness coefficients and allele frequencies from ancient samples

2017-01-28

Abstract excerpt

We develop and test a method to address whether DNA samples sequenced from a group of fossil hominin bone or teeth fragments originate from the same individual or from closely related individuals. Our method assumes low amounts of retrievable DNA, significant levels of sequencing error and contamination from one or more present-day humans. We develop and implement a maximum likelihood method that estimates levels...

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Identifiers and source

Literature Corpus work
538de2c2-1635-5257-b936-c2cc9de40ab6
DOI
10.1101/103903
Open publication

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Joint estimation of relatedness coefficients and allele frequencies from ancient samplesDOI 10.1101/103903
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