Article

EHE cell cultures: a platform for mechanistic and therapeutic investigation

2025-03-27

Abstract excerpt

Epithelioid hemangioendothelioma (EHE) is a difficult to treat vascular sarcoma defined by TAZ- CAMTA1 or YAP-TFE3 fusion proteins. Human cell lines needed to further understand the pathogenesis of EHE have been lacking. Herein, we describe a method to generate EHE extended primary cell cultures. An integrated multi –omic and functional approach was used to characterize these cultures. The cell cultures, relativel...

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Literature Corpus work: 8e271857-d3a0-5e61-bbdd-5dd9607c21bd
DOI: 10.1101/2025.03.24.644191

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