YAP1-TFE3-fused hemangioendothelioma: a multi-institutional clinicopathologic study of 24 genetically-confirmed cases.

doi:10.1038/s41379-021-00879-7

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Article

YAP1-TFE3-fused hemangioendothelioma: a multi-institutional clinicopathologic study of 24 genetically-confirmed cases.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2021

Dermawan Josephine K, Azzato Elizabeth M, Billings Steven D, Fritchie Karen J, Aubert Sebastien, Bahrami Armita, Barisella Marta, Baumhoer Daniel, Blum Veronika, Bode Beata, Aesif Scott W, Bovée Judith V M G, Dickson Brendan C, van den Hout Mari, Lucas David R, Moch Holger, Oaxaca Gabriel, Righi Alberto, Sciot Raf, Sumathi Vaiyapuri, Yoshida Akihiko, Rubin Brian P

Abstract excerpt

YAP1-TFE3-fused hemangioendothelioma is an extremely rare malignant vascular tumor. We present the largest multi-institutional clinicopathologic study of YAP1-TFE3-fused hemangioendothelioma to date. The 24 cases of YAP1-TFE3-fused hemangioendothelioma showed a female predominance (17 female, 7 male) across a wide age range (20-78 years old, median 44). Tumors were most commonly located in soft tissue (50%),...

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PMID: 34381186
DOI: 10.1038/s41379-021-00879-7

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