Epithelioid hemangioendothelioma ( EHE ) with WWTR1::TFE3 gene fusion, a novel fusion variant

Abstract excerpt

Epithelioid hemangioendothelioma (EHE) is a rare endothelial sarcoma associated with a high incidence of metastases and for which there are no standard treatment options. Based on disease-defining mutations, most EHEs are classified into two subtypes: WWTR1::CAMTA1-fused EHE or YAP1::TFE3-fused EHE. However, rare non-canonical fusions have been identified in clinical samples of EHE cases and are challenging to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cellular Mechanics and Interactions
• Share to Ubiquitin and proteasome pathways
• Share to Vascular Tumors and Angiosarcomas