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Article

Dissecting metabolic landscape of alveolar macrophage.

Scientific reports - 5 Dec 2024

Malla Sunayana, Sajeevan Karuna Anna, Acharya Bibek, Chowdhury Ratul, Saha Rajib

Abstract excerpt

The highly plastic nature of Alveolar Macrophage (AM) plays a crucial role in the defense against inhaled particulates and pathogens in the lungs. Depending on the signal, AM acquires either the classically activated M1 phenotype or the alternatively activated M2 phenotype. In this study, we investigate the metabolic shift in the activated phases of AM (M1 and M2 phases) by reconstructing context specific...

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Identifiers

PMID: 39638830
DOI: 10.1038/s41598-024-81253-w
PMCID: PMC11621776

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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