Article

Zinc finger antiviral protein (ZAP) activity in mammalian and avian hosts in CpG and UpA-mediated restriction of RNA viruses and investigation of ZAP-mediated shaping of host transcriptome compositions

2021-11-04

Abstract excerpt

<h4>ABSTRACT</h4> The ability of zinc finger antiviral protein (ZAP) to recognise and respond to RNA virus sequences with elevated frequencies of CpG dinucleotides has been proposed as a functional part of the vertebrate innate immune antiviral response. It has been further proposed that ZAP activity shapes compositions of cytoplasmic mRNA sequences to avoid self-recognition, particularly mRNAs for interferons (I...

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Literature Corpus work: 8de05c8f-0ecf-5493-b032-e4eed69fc230
DOI: 10.1101/2021.11.04.467232

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