Article

The long non-coding RNA LINC00941 modulates MTA2/NuRD occupancy to suppress premature human epidermal differentiation

2023-07-25

Abstract excerpt

Numerous long non-coding RNAs (lncRNAs) were shown to have functional impact on cellular processes such as human epidermal homeostasis. However, the mechanism of action for many lncRNAs remains unclear to date. Here, we report that lncRNA LINC00941 regulates keratinocyte differentiation on an epigenetic level through association with the NuRD complex, one of the major chromatin remodelers in cells. We find that LI...

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Literature Corpus work: 8d9d86fc-8cf6-57cf-a5d1-4ea0526fed03
DOI: 10.1101/2023.07.25.549662

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