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Article

SNAI2 Controls the Undifferentiated State of Human Epidermal Progenitor Cells

7 Aug 2014

Abstract excerpt

The transcription factor, SNAI2, is an inducer of the epithelial to mesenchymal transition (EMT) which mediates cell migration during development and tumor invasion. SNAI2 can also promote the generation of mammary epithelial stem cells from differentiated luminal cells when overexpressed. How SNAI2 regulates these critical and diverse functions is unclear. Here, we show that the levels of SNAI2 expression are...

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PMID: 25100569
DOI: 10.1002/stem.1809

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