Article

Involvement of transcribed lncRNA uc.291 in hyperproliferative skin disorders

2023-11-07

Abstract excerpt

The uc.291 transcript controls keratinocytes differentiation by physical interaction with ACTL6A and subsequent induction of transcription of the genes belonging to the epidermal differentiation complex (EDC). Uc.291 is also implicated in the dedifferentiation phenotype seen in poorly differentiated cutaneous squamous cell carcinomas. Here, we would like to investigate the contribution of uc.291 to the unbalanced...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4f1795ba-d5c2-5e2e-a437-62fc0559384f
DOI: 10.21203/rs.3.rs-3544643/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Involvement of transcribed lncRNA uc.291 in hyperproliferative skin disordersDOI 10.21203/rs.3.rs-3544643/v1Read

RNA Sequencing Reveals the Long Non‐Coding RNA Signature in Psoriasis Keratinocytes and Identifies CYDAER as a Long Non‐Coding RNA Regulating Epidermal DifferentiationSemantic proximity Read

Genome-Wide Differential Transcription of Long Noncoding RNAs in Psoriatic SkinSemantic proximity Read

Review—Current Concepts in Inflammatory Skin Diseases Evolved by Transcriptome Analysis: In-Depth Analysis of Atopic Dermatitis and PsoriasisSemantic proximity Read

Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skinSemantic proximity Read

Potential Role of the Epidermal Differentiation Complex in the Pathogenesis of PsoriasisSemantic proximity Read

Transcriptomic Profiling of Peripheral Edge of Lesions to Elucidate the Pathogenesis of Psoriasis VulgarisSemantic proximity Read

RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skinSemantic proximity Read

Meta-analysis of RNA sequencing data from 534 skin samples shows substantial IL-17 effects in non-lesional psoriatic skinSemantic proximity Read

Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RNSemantic proximity Read

Integrative single-cell transcriptomic investigation unveils long non-coding RNAs associated with localized cellular inflammation in psoriasisSemantic proximity Read

Transcriptome Profiling Analyses in Psoriasis: A Dynamic Contribution of Keratinocytes to the PathogenesisSemantic proximity Read

SKINOMICS: Transcriptional Profiling in Dermatology and Skin BiologySemantic proximity Read