Article
Control of somatic tissue differentiation by the long non-coding RNA TINCR.
Nature - 10 Jan 2013
Kretz Markus, Siprashvili Zurab, Chu Ci, Webster Dan E, Zehnder Ashley, Qu Kun, Lee Carolyn S, Flockhart Ross J, Groff Abigail F, Chow Jennifer, Johnston Danielle, Kim Grace E, Spitale Robert C, Flynn Ryan A, Zheng Grace X Y, Aiyer Subhadra, Raj Arjun, Rinn John L, Chang Howard Y, Khavari Paul A
Abstract excerpt
Several of the thousands of human long non-coding RNAs (lncRNAs) have been functionally characterized; however, potential roles for lncRNAs in somatic tissue differentiation remain poorly understood. Here we show that a 3.7-kilobase lncRNA, terminal differentiation-induced ncRNA (TINCR), controls...
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