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Current Techniques of Gene Editing in Pigs for Xenotransplantation

27 May 2025

Abstract excerpt

Shortage of human organs for transplantation has created a demand for alternative solutions of which xenotransplantation is amongst the most promising one in the short term. However, the immune reaction following transplantation of a pig organ is greater than the one elicited during allotransplantation. Genetic engineering of the pig is required so that pig organs or tissues are made less immunogenic to humans by...

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Identifiers

PMID: 40497031
DOI: 10.3389/ti.2025.13807

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