Article

Off-target-free chemogenetic platform that decodes physiological roles of target GPCRs

2026-05-27

Abstract excerpt

<h4>SUMMARY</h4> G-protein-coupled receptors (GPCRs) are essential mediators of cellular processes, and their dysfunction is implicated in various diseases. Although pharmacological approaches are powerful for elucidating GPCR functions, careful consideration of potential off-target effects remains crucial. Here, we present an off-target-free chemogenetic platform to dissect the physiological roles of target GPCR...

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Literature Corpus work: 3a03d016-6421-50be-abe8-db16fb1bc45b
DOI: 10.64898/2026.05.24.727545

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