Article

XPC restrains cancer stemness by modulating STAT1-SOX2 signaling in non-small cell lung cancer

2026-03-26

Abstract excerpt

<title>Abstract</title> <p>Cancer stem cells (CSCs) drive tumor initiation, therapeutic resistance, and disease relapse, yet the molecular mechanisms sustaining CSC maintenance remain incompletely defined. Xeroderma pigmentosum complementation group C (XPC) is a core DNA damage recognition factor in nucleotide excision repair, and its loss is linked to cancer predisposition. Beyond its canonical role in genome ma...

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Literature Corpus work: 8cfddbac-0513-58ab-9e82-5e4765b3cb2d
DOI: 10.21203/rs.3.rs-9002641/v1

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