Article

<i>Ggnbp2</i> regulates synaptic development and autophagy in motor neurons

2023-11-04

Abstract excerpt

<h4> Abstract </h4> Genome-wide association studies (GWAS) have identified numerous candidate ALS risk variants, but their cellular functions are often unknown. Recent studies have identified a variant of GGNBP2 that results in increased expression. To better understand how this gene might contribute to disease, we investigated the function of Drosophila Ggnbp2 (dGgnbp2) in motor neurons. Loss of function stud...

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Literature Corpus work: 8cfa9b94-aba0-55ca-b080-f6f2abc74935
DOI: 10.1101/2023.11.03.565470

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