Article

Comparison of mouse models reveals a molecular distinction between psychotic illness in PWS and schizophrenia

2021-01-26

Abstract excerpt

<h4>ABSTRACT</h4> Prader-Willi Syndrome (PWS) is a neurodevelopmental disorder caused by mutations affecting paternal chromosome 15q11-q13, and characterized by hypotonia, hyperphagia, impaired cognition and behavioural problems. Psychotic illness is a challenging problem for individuals with PWS and has different rates of prevalence in distinct PWS genotypes. Previously, we demonstrated behavioural and cognitive...

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Literature Corpus work: 8cf8087d-1ad2-5cb9-9723-03cf57408333
DOI: 10.1101/2021.01.26.428232

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