Article
Prader-Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain.
Gene expression patterns : GEP - 1 Oct 2003
Lee Syann, Walker Christine L, Wevrick Rachel
Abstract excerpt
Prader-Willi syndrome (PWS) is a neurobehavioral disorder that is due to the loss of multiple, paternally-expressed, imprinted genes on human chromosome 15q11-q13. The candidate genes are conserved in mice and are located in an orthologous region on mouse 7C. Several mouse models in which one or more of the PWS candidate genes are silenced do not recapitulate the full PWS phenotype. We examined the expression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
