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miRNome profiling of clonal stem cells in Ph <sup>+</sup> CML

2020-03-18

Abstract excerpt

Chronic myeloid leukemia (CML) is a myeloid stem cell neoplasm characterized by an expansion of myeloid progenitor cells and the presence of BCR-ABL1 oncoprotein. Since the introduction of specific BCR-ABL1 tyrosine kinase inhibitors (TKI), overall survival has improved significantly. However, under long-term therapy patients may have residual disease that originates from TKI-resistant leukemic stem cells (LSC). I...

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Literature Corpus work
8cd23ded-7cdc-5ba8-9d5b-8ada23646104
DOI
10.1101/2020.03.16.989194
Open publication

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miRNome profiling of clonal stem cells in Ph <sup>+</sup> CMLDOI 10.1101/2020.03.16.989194
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