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High circ_100053 predicts a poor outcome for chronic myeloid leukemia and is involved in imatinib resistance

1 Jan 2019

Abstract excerpt

Chronic myeloid leukemia (CML) is a rare clonal myeloproliferative malignancy, which is caused by a reciprocal translocation between chromosomes 9 and 22 t(9;22) (q34;q11). Altered circle RNAs (circRNAs) could contribute to leukemogenesis. In this study, we aimed to investigate the expression profiling of circRNAs in CML. We performed circRNA-sequencing to identify differentially expressed circRNAs in CML cells....

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PMID: 30764894
DOI: 10.3727/096504018x15412701483326

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