Article

A whole organism screening platform identifies gut microbiome microproteins that modulate host metabolism

2026-02-12

Abstract excerpt

Advances in metagenomic sequencing over the past two decades have identified vast numbers of previously uncharacterised small open reading frames that may encode microproteins (<50aa). Although computational tools have accelerated gene sequence prediction from metagenomic data, the function of most annotated proteins remains unknown and untested, especially in the context of host-microbiome interactions. Here, we...

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Literature Corpus work: 8c872771-ded8-5377-94e4-2a8f5abe06f1
DOI: 10.64898/2026.02.11.705328

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