Article

Systematic Metaproteomics Mapping Reveals Functional and Ecological Landscapes of Ex Vivo Human Gut Microbiota Responses to Therapeutic Drugs

2025-02-14

Abstract excerpt

Therapeutic compounds exert impacts on gut microbiota; however, how they affect the community functional ecology, especially as reflected at the protein level, remains largely unexplored. In this study, we systematically map metaproteomic responses of ex vivo human gut microbiota to 312 compounds, generating 4.6 million microbial protein responses, available as an interactive resource ( https://shiny.imetalab.ca...

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Literature Corpus work: 4fc1fba6-2ba8-5933-b28d-1dd5a7e35328
DOI: 10.1101/2025.02.13.637346

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