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Identification of MRP1 and its role in complete remission (CR) after induction therapy in Acute Myeloid Leukemia patients. 

2022-09-02

Abstract excerpt

Adenosine triphosphate (ATP) binding transporters are one of the chief reason behind drug resistance. There are forty nine adenosine triphosphate binding cassette (ABC) transporters. Some of them are Multidrug resistance associated protein-1 (MRP 1), Breast resistance cancer protein (BCRP), and P glycoprotein (P-gp). Their expression in the cell causes expel out of drugs from the cell. Therefore, the patient is in...

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Literature Corpus work
8c74b560-0671-54b4-bf0a-31cd172cf155
DOI
10.21203/rs.3.rs-2002513/v1
Open publication

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