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New Δ246p53 isoform responds to DNA damage to enhance p53 family functions in cellular senescence

2023-04-08

Abstract excerpt

<h4>ABSTRACT</h4> p53 is with little doubt one of the most powerful genes in our genome, as it makes growth vs arrest, repair vs replacement, catabolism vs anabolism, life vs death decisions in the cell. An alteration or malfunction in p53 may lead to cancer, degeneration or premature ageing. So, it is not surprising that p53 is also one of the most complex and tightly regulated genes, encoding for at least...

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Identifiers and source

Literature Corpus work
8c707228-ab96-5a97-b71b-b1b74d6f2a05
DOI
10.1101/2023.04.07.536059
Open publication

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New Δ246p53 isoform responds to DNA damage to enhance p53 family functions in cellular senescenceDOI 10.1101/2023.04.07.536059
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