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Article

The Emerging Landscape of p53 Isoforms in Physiology, Cancer and Degenerative Diseases.

International journal of molecular sciences - 11 Dec 2019

Anbarasan Thineskrishna, Bourdon Jean-Christophe

Abstract excerpt

p53, first described four decades ago, is now established as a master regulator of cellular stress response, the "guardian of the genome". p53 contributes to biological robustness by behaving in a cellular-context dependent manner, influenced by several factors (e.g., cell type, active signalling pathways, the type, extent and intensity of cellular damage, cell cycle stage, nutrient availability, immune...

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Identifiers

PMID: 31835844
DOI: 10.3390/ijms20246257
PMCID: PMC6941119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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