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Article

In-silico evidences on filarial cystatin as a putative ligand of human TLR4

6 May 2021

Abstract excerpt

Cystatin is a small molecular weight immunomodulatory protein of filarial parasite that plays a pivotal role in downregulating the host immune response to prolong the survival of the parasite inside the host body. Hitherto, this protein is familiar as an inhibitor of human proteases. However, growing evidences on the role of cystatin in regulating inflammatory homeostasis prompted us to investigate the molecular...

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PMID: 33955317
DOI: 10.1080/07391102.2021.1918252

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