Article

Evaluation of single-cell RNA profiling technologies using FFPE, fresh, and frozen ccRCC tumor specimens

2025-11-28

Abstract excerpt

<h4>ABSTRACT</h4> The application of single-cell transcriptomic approaches has deepened our understanding of tumor heterogeneity, immune dynamics, and molecular programs underlying therapy response. The recent development of fixation-compatible single-cell platforms, such as 10x Genomics Flex, offers the opportunity to profile archived formalin-fixed, paraffin-embedded (FFPE) specimens, expanding access to clinic...

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Literature Corpus work: fed9d576-5e45-531f-935f-4085f9c4d988
DOI: 10.1101/2025.11.25.690485

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