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Infant CD4 T-cell response to SARS-CoV-2 mRNA vaccination is restricted in cytokine production and modified by vaccine manufacturer

2025-04-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Safe and effective vaccines are a key preventative measure to protect infants from SARS-CoV-2 infection and disease. Although mRNA vaccines induce robust antibody titers in infants, little is known about the quality of CD4 T-cell responses induced by vaccination. CD4 T-cell responses are important in orchestrating coordinated immune responses during infection and may help to...

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Literature Corpus work
8be7997f-e527-5de9-b288-748a9c6a59ee
DOI
10.1101/2025.04.02.646864
Open publication

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Infant CD4 T-cell response to SARS-CoV-2 mRNA vaccination is restricted in cytokine production and modified by vaccine manufacturerDOI 10.1101/2025.04.02.646864
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