Article

Preserved T-Cell Immunity Despite Impaired Humoral Responses following SARS-CoV-2 Infection and Vaccination in Children with Profound B-cell Lymphopenia

2026-03-08

Abstract excerpt

<title>Abstract</title> <p> Understanding the mechanisms of vaccine-induced protection in children with humoral immunodeficiency is essential to guide prevention strategies and reduce COVID-19-related complications and mortality. Yet, comprehensive cellular, humoral and mucosal analyses are scarce in this high-risk population. We conducted a longitudinal evaluation of SARS-CoV-2 immunity at 1, 6 and 12 months af...

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Literature Corpus work: 4e08aa32-a55d-5a35-9299-c25bec6a3b61
DOI: 10.21203/rs.3.rs-8864462/v1

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