Article
Gametocytogenesis-enhancing drug combinations can facilitate artemisinin resistance despite better clinical outcomes
2022-09-28
Abstract excerpt
<h4>Background: </h4> Malaria eradication goals are threatened by the spread of artemisinin resistance, which is an evolutionary process. The selective advantage of mutations in Plasmodium falciparum conferring tolerance or even resistance is determined as the probability of their successful transmission. The drug’s efficacy in clearing merozoites is the main determinant for the clinical pathogenesis, but only one...
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Identifiers and source
- Literature Corpus work
- 8be73abc-9702-5b7b-a9f8-d01d77f702bd
- DOI
- 10.21203/rs.3.rs-2097852/v1