Article

Pre-existing partner-drug resistance facilitates the emergence and spread of artemisinin resistance: a consensus modelling study

2021-04-10

Abstract excerpt

<h4>Background</h4> Artemisinin-resistant genotypes have now emerged a minimum of five times on three continents despite recommendations that all artemisinins be deployed as artemisinin combination therapies (ACTs). Widespread resistance to the non-artemisinin partner drugs in ACTs has the potential to limit the clinical and resistance benefits provided by combination therapy. <h4>Methods</h4> Using a consensus...

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Literature Corpus work: bfd3e141-2896-5931-aec7-3e25609565b7
DOI: 10.1101/2021.04.08.437876

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