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Design and selection of drug properties to increase the public health impact of next-generation seasonal malaria chemoprevention: a modelling study

2023-10-13

Abstract excerpt

<h4>Background</h4> Seasonal malaria chemoprevention (SMC) is recommended for disease control in settings with moderate to high Plasmodium falciparum transmission and currently depends on administration of sulfadoxine-pyrimethamine with amodiaquine. However, poor regimenadherence and the increasedfrequencyof sulfadoxine-pyrimethamine resistant parasite mutations may threaten SMC’s effectiveness. We need guidance t...

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Literature Corpus work
2ad66a97-3291-5261-bf7a-14ffd34a808a
DOI
10.1101/2023.10.13.23292651
Open publication

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