Article

Identification of risk and protective human leukocyte antigens in COVID-19 using genotyping and structural modeling

2021-05-08

Abstract excerpt

COVID-19 is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The severity of COVID-19 is highly variable and related to known (e.g., age, obesity, immune deficiency) and unknown risk factors. Since innate and adaptive immune responses are elicited in COVID-19 patients, we genotyped 94 Florida patients with confirmed COVID-19 and 89 healthy controls. We identified an HLA gene, HLA-DPA1, in wh...

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Literature Corpus work: 8b574eb8-16c9-59c5-acf7-75261899ca5f
DOI: 10.1101/2021.05.04.21256636

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