Article
The association of human leucocyte antigen (HLA) alleles with COVID-19 severity: A systematic review and meta-analysis.
Reviews in medical virology - 1 Jan 2023
Dobrijević Zorana, Gligorijević Nikola, Šunderić Miloš, Penezić Ana, Miljuš Goran, Tomić Sergej, Nedić Olgica
Abstract excerpt
Due to their pivotal role in orchestrating the immune response, HLA loci were recognized as candidates for genetic association studies related to the severity of COVID-19. Since the findings on the effects of HLA alleles on the outcome of SARS-CoV-2 infection remain inconclusive, we aimed to elucidate the potential involvement of genetic variability within HLA loci in the molecular genetics of COVID-19 by...
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