HLA-A*11:01 and HLA-C*04:01 are associated with severe COVID-19.

doi:10.1111/tan.15160

Article

HLA-A11:01 and HLA-C04:01 are associated with severe COVID-19.

HLA - 1 Dec 2023

Castro-Santos Patricia, Rojas-Martinez Augusto, Riancho José A, Lapunzina Pablo, Flores Carlos, Carracedo Ángel, Díaz-Peña Roberto

Abstract excerpt

We analyzed the association between HLA polymorphisms and susceptibility to SARS-CoV-2 infection and disease severity. Genotyping data from a total of 9373 COVID-19-positive cases from the Spanish Coalition to Unlock Research on Host Genetics on COVID-19 (SCOURGE) consortium and 5943 population c...

Topics

Humans
COVID-19
HLA-C Antigens
SARS-CoV-2
Gene Frequency
Alleles
HLA-A Antigens

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.