Article
HLA class I associations with the severity of COVID-19 disease in the United Arab Emirates.
PloS one - 1 Jan 2023
Tay Guan K, Alnaqbi Halima, Chehadeh Sarah, Peramo Braulio, Mustafa Farah, Rizvi Tahir A, Mahboub Bassam H, Uddin Maimunah, Alkaabi Nawal, Alefishat Eman, Jelinek Herbert F, Alsafar Habiba
Abstract excerpt
SARS-CoV-2 appears to induce diverse innate and adaptive immune responses, resulting in different clinical manifestations of COVID-19. Due to their function in presenting viral peptides and initiating the adaptive immune response, certain Human Leucocyte Antigen (HLA) alleles may influence the susceptibility to severe SARS-CoV-2 infection. In this study, 92 COVID-19 patients from 15 different nationalities, with...
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