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Neutrophil Transcriptomics in SLE: Exploring Intrinsic, Ex Vivo Adaptation, and CAR T-Cell Therapy-Induced Changes

2025-11-05

Abstract excerpt

<h4>Objectives</h4> Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by dysregulation of the adaptive and innate immunityThis study aimed to identify transcriptomic differences in neutrophils from SLE patients and healthy individuals, analyze ex vivo adaptation dynamics, and evaluate the impact of chimeric antigen receptor (CAR) T-cell therapy on neutrophil transcriptomic profiles. <h4>Me...

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Literature Corpus work
8b2af5b4-5df1-5368-85ec-1e453dcd5a3a
DOI
10.1101/2025.11.03.686294
Open publication

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Neutrophil Transcriptomics in SLE: Exploring Intrinsic, Ex Vivo Adaptation, and CAR T-Cell Therapy-Induced ChangesDOI 10.1101/2025.11.03.686294
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