Article
Single amino acid mutations effect Zika virus replication <i>in vitro</i> and virulence <i>in vivo</i>
2020-08-06
Abstract excerpt
The 2014-2016 Zika virus (ZIKV) epidemic in the Americas resulted in large deposits of next-generation sequencing data from clinical samples. This resource was mined to identify emerging mutations and trends in mutations as the outbreak progressed over time. Information on transmission dynamics, prevalence and persistence of intra-host mutants, and the position of a mutation on a protein were then used to prioriti...
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Identifiers and source
- Literature Corpus work
- 8b27d16d-8123-51cf-8ca5-64101d2c99f9
- DOI
- 10.1101/2020.08.06.239392