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Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone

20 Oct 2016

Abstract excerpt

Zika virus (ZIKV; family Flaviviridae, genus Flavivirus) is a rapidly expanding global pathogen that has been associated with severe clinical manifestations, including devastating neurological disease in infants. There are currently no molecular clones of a New World ZIKV available that lack significant attenuation, hindering progress toward understanding determinants of transmission and pathogenesis. Here we...

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PMID: 27795432
DOI: 10.1128/jvi.01765-16

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