Article

Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis

2020-01-03

Abstract excerpt

Liquid biopsy using cell-free DNA (cfDNA) is attractive for a wide range of clinical applications, including cancer detection, locating, and monitoring. However, developing these applications requires precise and sensitive calling of somatic single nucleotide variations (SNVs) from cfDNA sequencing data. To date, no SNV caller addresses all the special challenges of cfDNA to provide reliable results. Here we prese...

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Literature Corpus work: 8b05fe6c-6a1d-59fd-af94-aa61f118b83f
DOI: 10.1101/2019.12.31.19016253

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