Article

Mouse xenograft models for elucidating drug resistance mechanisms

2017-02-06

Abstract excerpt

Divergence of treatment responses to chemotherapy exists across patients (often with unknown underlying mechanisms), with some patients exhibiting worsened outcome upon treatment. Genomic approaches (such as microarray profiling and whole genome sequencing) hold promise for transforming cancer treatment, particularly, in tailoring drug regimen to specific patients. Nevertheless, formulating effective personalized...

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Literature Corpus work: 8b05c704-fff9-5524-a2ea-a731bb3fb784
DOI: 10.7287/peerj.preprints.1049v6

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