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Comparative Analysis of Chemotherapy Resistance Mechanisms in Humans and Companion Animals

12 Aug 2025

Abstract excerpt

The transition from a normal to a cancerous cell involves a multistep process driven by genetic alterations. Malignant cells progressively acquire traits that enhance their survival within the host, including the ability to evade apoptosis, stimulate neovascularization, and escape immune surveillance. These adaptations allow cancer to grow uncontrollably, invade adjacent tissues, and metastasize to distant...

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PMID: 40872698
DOI: 10.3390/vetsci12080747

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