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Drug resistance in the mouse cancer clinic

1 Feb 2012

Abstract excerpt

Drug resistance is one of the most pressing problems in treating cancer patients today. Local and regional disease can usually be adequately treated, but patients eventually die from distant metastases that have become resistant to all available chemotherapy. Although work on cultured tumor cell lines has yielded a lot of information on potential drug resistance mechanisms, it has proven difficult to translate...

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PMID: 22335919
DOI: 10.1016/j.drup.2012.01.001

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