Article
Animal modeling of cancer pathology and studying tumor response to therapy.
Current drug targets - 1 Nov 2012
Langdon Simon P
Abstract excerpt
Animal models of human cancer have evolved in attempts to capture the complexity of the human disease. They encompass two broad types of model, namely those in which the tumor arises in situ and those in which cancer cells or tissue are transplanted. Currently human tumor xenografts are the most widely used model to help predict antitumor efficacy in a preclinical setting and xenograft results for certain disease...
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