Article

The Cappuccino interactome reveals an intracellular role for Semaphorin-2a in Drosophila oogenesis

2026-05-14

Abstract excerpt

The spatiotemporal regulation of an actin mesh during Drosophila oogenesis is essential for proper localization of cell polarity determinants that establish the future patterning of the embryo. Here, we reveal an unexpected role for Semaphorin-2a (Sema2a) in actin mesh regulation and oogenesis. Sema2a classically functions as a secreted guidance cue that binds its cognate Plexin-B (PlexB) receptor to establish neu...

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Literature Corpus work: 8adda6e8-b27e-5b35-ae3a-af9271474387
DOI: 10.64898/2026.05.11.724452

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