Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Innexin2 gap junctions in somatic support cells are required for cyst formation and for egg chamber formation in Drosophila.

Mechanisms of development - 1 Jan 2000

Mukai Masanori, Kato Hirotaka, Hira Seiji, Nakamura Katsuhiro, Kita Hiroaki, Kobayashi Satoru

Abstract excerpt

Germ cells require intimate associations with surrounding somatic cells during gametogenesis. During oogenesis, gap junctions mediate communication between germ cells and somatic support cells. However, the molecular mechanisms by which gap junctions regulate the developmental processes during oogenesis are poorly understood. We have identified a female sterile allele of innexin2 (inx2), which encodes a gap...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadherins
Share to Cell Adhesion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Connexins

Share to Gap Junctions

Share to Germ Cells

Share to Infertility, Female

Share to Oogenesis

Share to Organogenesis

Source

Identifiers

PMID: 22001874
DOI: 10.1016/j.mod.2011.09.005

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Innexin2 gap junctions in somatic support cells are required for cyst formation and for egg chamber formation in Drosophila.PMID 22001874Read ↗

Two classes of gap junction channels mediate soma-germline interactions essential for germline proliferation and gametogenesis in Caenorhabditis elegans.Semantic proximity Read ↗

The role of gap junctions in Caenorhabditis elegans oocyte maturation and fertilization.Semantic proximity Read ↗

A tug-of-war between germ cell motility and intercellular bridges controls germline cyst formation in miceSemantic proximity Read ↗

CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytiaSemantic proximity Read ↗

Mouse germ cell clusters form by aggregation as well as clonal divisions.Semantic proximity Read ↗

Branched germline cysts and female-specific cyst fragmentation facilitate oocyte determination in miceSemantic proximity Read ↗

The Caenorhabditis elegans innexin INX-3 is localized to gap junctions and is essential for embryonic development.Semantic proximity Read ↗

Daughterless coordinates somatic cell proliferation, differentiation and germline cyst survival during follicle formation in Drosophila.Semantic proximity Read ↗

N-Cadherin Is Critical for the Survival of Germ Cells, the Formation of Steroidogenic Cells, and the Architecture of Developing Mouse GonadsSemantic proximity Read ↗

A somatic permeability barrier around the germline is essential for<i>Drosophila</i>spermatogenesisSemantic proximity Read ↗

Mutations that Affect Channel Opening of Innexin Hemichannels in the C. elegans GonadSemantic proximity Read ↗

Endogenous Nodal signaling regulates germ cell potency during mammalian testis developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.