Article
Growth Arrest Specific 2 (GAS2) is a Critical Mediator of Germ Cell Cyst Breakdown and Folliculogenesis in Mice.
Scientific reports - 13 Oct 2016
York J Philippe, Ren Yi Athena, Zeng Jie, Bin Zhang, Wang Fang, Chen Rui, Liu Jianqiao, Xia Xuefeng, Zhang Pumin
Abstract excerpt
In the mouse ovary, the primordial follicle pool is established through a diverse array of signaling pathways and tissue remodeling events. Growth arrest specific gene two (GAS2) is a highly conserved cytoskeleton-associated protein whose in vivo function remains unclear. In Drosophila, loss of the GAS2 homolog, Pigs, results in infertility. We demonstrate herein that, in the mouse ovary, GAS2 is expressed in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.