Article
Profilin is required for posterior patterning of the Drosophila oocyte.
Development (Cambridge, England) - 1 Jul 1996
Manseau L, Calley J, Phan H
Abstract excerpt
We have investigated the role of the actin cytoskeleton during mid-oogenesis and have found that disrupting the actin cytoskeleton with cytochalasin D induces microtubule bundling and microtubule-based cytoplasmic streaming within the oocyte, similar to that which occurs prematurely in cappuccino and spire mutant oocytes. After examining a number of mutants that affect the actin cytoskeleton, we have found that...
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