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Germinal center activity and B cell maturation promote protective antibody responses against <i>Plasmodium</i> pre-erythrocytic infection

2021-09-11

Abstract excerpt

Blocking Plasmodium , the causative agent of malaria, at the asymptomatic pre-erythrocytic stage would abrogate disease pathology and prevent transmission. Rodent-infectious species of Plasmodium such as P. yoelii (Py) serve as key tools to study vaccine efficacy and disease biology in immune-competent experimental animals. Here we evaluated the differences in vaccine-elicited humoral immunity in two widely use...

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Literature Corpus work
8acc20e2-a923-5625-8f09-ada52e15e8ab
DOI
10.1101/2021.09.10.459481
Open publication

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Germinal center activity and B cell maturation promote protective antibody responses against <i>Plasmodium</i> pre-erythrocytic infectionDOI 10.1101/2021.09.10.459481
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